The influence of environmental and genetic factors in the manifestation of dissocial disorder

Abstract

There are several etiological theories for Dissocial Personality Disorder (DPD), which integrate organic, social, cultural, emotional, educational, genetic and environmental issues. Among them, the relationship between personality and serotonin transporter polymorphisms (5-HTT) and the occurrence of anxiety and depressive symptoms, as well as the relationship with climacteric and menopause; these and others are bidirectionally integrated with the environment. In order to discuss the influence of environmental and genetic factors in the manifestation of DPD, we made a narrative review using articles from the National Library of Medicine (PubMed), Scientific Electronic Library Online (SciELO), and Latin Literature databases -American and Caribbean in Health Sciences (LILACS) and “Academic Google”, published from 2009 to 2021, with the descriptors and keywords, with the Boolean operator “and”, “Etiology”; “Genetics”; "Environment"; “Classification of mental and behavioral disorders”; “International Classification of Diseases”; “Diagnostic and Statistical Manual of Mental Disorders”; “ICD-10”; “ICD-11”; “DSM-5”; “Antisocial Personality Disorder”; “Dissocial Personality Disorder”; “Sociopathic personality disorder”; “Shyness”; "Psychopathology". The study was divided into 3 topics: Classification of personality disorders by ICD-10, ICD-11 and DSM-5; Etiologies of personality disorders and Environmental and genetic factors as etiologies of Dissocial Personality Disorder. We concluded that environmental, genetic and other factors integrate and act in different ways, in different people, in the etiology of DPD.